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A recent animal study was published in April 2008 in the "British Journal of Pharmacology. Goat's rue is not approved for diabetes treatment by the U. Food and Drug Administration or Germany's Commission E, a scientific advisory board that reviews and approves herbal medicines. Commission E noted significant health risks with goat's rue and the availability of more effective diabetes treatments. Importantly, animal studies show that goat's rue may be harmful during pregnancy. Bitter Melon Bitter melon has long been used as a folk remedy for diabetes. Several substances found in the fruit and seeds of bitter melon reportedly have blood-sugar-lowering effects. However, research on the effectiveness of bitter melon as a diabetes remedy has been mixed. A February 2002 "Alternative Medicine Review" article reported that 2 small studies conducted in people with diabetes suggested blood-sugar-lowering effects.
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The researchers cautioned, however, that the quality of the studies was generally poor, which could lead to inaccurate conclusions. Large, well-designed studies are needed to determine whether berberine may be useful for diabetes treatment. It is not FDA-approved for diabetes treatment as of 2016. Large doses of berberine may cause digestive system upset, flulike symptoms, shortness of breath and low blood pressure. It may also increase the risk for miscarriage by stimulating uterine contractions. Cinnamon Cinnamon has also been suggested as a possible herbal treatment for diabetes. A September 2013 "Annals of Family Medicine" article examined the pooled results from 10 studies wherein 543 people with T2DM took daily cinnamon or an inactive placebo for 4 to 18 weeks. Many study participants also took oral diabetes medicines. The researchers found that participants taking cinnamon had lower fasting blood sugar levels than those taking a placebo.
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